منابع مشابه
PIH proteins give dynein arms a hand
Long asters rock the spindle M itotic cells regulate the lengths of their astral microtubules to keep the spindle steady during cytokine-sis, Rankin and Worde-man report. Astral microtu-bules emanate from the spindle poles toward the cell cortex and help to position the cleavage furrow at the end of mitosis by confi ning actomyosin contraction to the cell equator: when microtubules are shortene...
متن کاملA motile Chlamydomonas flagellar mutant that lacks outer dynein arms
A new Chlamydomonas flagellar mutant, pf-28, which swims more slowly than wild-type cells, was selected. Thin-section electron microscopy revealed the complete absence of outer-row dynein arms in this mutant, whereas inner-row arms and other axonemal structures appeared normal. SDS PAGE analysis also indicated that polypeptides previously identified as outer-arm dynein components are completely...
متن کاملThe Inner Dynein Arms 12 Interact with a "Dynein Regulatory Complex" in Chlamydomonas Flagella
We provide indirect evidence that six axonemal proteins here referred to as "dynein regulatory complex" (drc) are located in close proximity with the inner dynein arms 12 and 13. Subsets of drc subunits are missing from five second-site suppressors, pf2, p f3, suppI3, suD:4, and suppz 5, that restore flagellar motility but not radial spoke structure of radial spoke mutants. The absence of drc c...
متن کاملThe inner dynein arms I2 interact with a "dynein regulatory complex" in Chlamydomonas flagella
We provide indirect evidence that six axonemal proteins here referred to as "dynein regulatory complex" (drc) are located in close proximity with the inner dynein arms I2 and I3. Subsets of drc subunits are missing from five second-site suppressors, pf2, pf3, suppf3, suppf4, and suppf5, that restore flagellar motility but not radial spoke structure of radial spoke mutants. The absence of drc co...
متن کاملLack of dynein arms in immotile human spermatozoa
Sermatozoa from two brothers who are not twins were found to be straight and immotile. Examinations of the sperm showed that oxygen consumption and lactic acid production were normal; viability tests showed that the percentage of dead sperm was not increased. The ultrastructural appearance of the sperm tail was normal except for a complete lack of dynein arms and some irregularities in the arra...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2010
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1901iti3